J Randolph Hecht : rechercher sur Z-Library

Le plus grand référentiel d'articles scientifiques au monde. 70,000,000+ d'articles gratuitement.

Don't use scam websites

Livres
Articles (49)
Les plus populaires
Liste
- Liste
- Tableau

1

A Phase III Randomized, Open-Label, Controlled Trial of Chemotherapy and Bevacizumab with or Without Panitumumab in the First-Line Treatment of Patients with Metastatic Colorectal Cancer

Zev Wainberg, J. Randolph Hecht

Journal:

Clinical Colorectal Cancer

Année:

2006

Langue:

english

Fichier:

PDF, 90 KB

english, 2006

2

A Randomized, Placebo-Controlled Phase II Study Evaluating the Reduction of Neutropenia and Febrile Neutropenia in Patients With Colorectal Cancer Receiving Pegfilgrastim With Every-2-Week Chemotherapy

J. Randolph Hecht, Madhavan Pillai, Russell Gollard, William Heim, Forrest Swan, Ravi Patel, Lyndah Dreiling, May Mo, Imtiaz Malik

Journal:

Clinical Colorectal Cancer

Année:

2010

Langue:

english

Fichier:

PDF, 561 KB

english, 2010

3

SPIRITT: A Randomized, Multicenter, Phase II Study of Panitumumab with FOLFIRI and Bevacizumab with FOLFIRI as Second-Line Treatment in Patients with Unresectable Wild Type KRAS Metastatic Colorectal Cancer

Hecht, J. Randolph, Cohn, Allen, Dakhil, Shaker, Saleh, Mansoor, Piperdi, Bilal, Cline-Burkhardt, Mika, Tian, Ying, Go, William Y.

Journal:

Clinical Colorectal Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 926 KB

english, 2015

4

Prolonged nausea and vomiting after high dose chemotherapy and autologous peripheral stem cell transplantation in the treatment of high risk breast carcinoma

J. Randolph Hecht, Tony Lembo, Linnea Chap

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 90 KB

english, 1997

5

Phase II trial of irinotecan in combination with amifostine in patients with advanced colorectal carcinoma

Maria L. Delioukina, Diane Prager, Mandy Parson, J. Randolph Hecht, Peter Rosen, Lee S. Rosen

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 71 KB

english, 2002

6

An open-label, multinational, multicenter study of G17DT vaccination combined with cisplatin and 5-fluorouracil in patients with untreated, advanced gastric or gastroesophageal cancer : The GC4 study

Jaffer A. Ajani, J. Randolph Hecht, Linus Ho, Jackie Baker, Marga Oortgiesen, Arnavaz Eduljee, Dov Michaeli

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 247 KB

english, 2006

7

Panitumumab monotherapy in patients with previously treated metastatic colorectal cancer

J. Randolph Hecht, Amita Patnaik, Jordan Berlin, Alan Venook, Imtiaz Malik, Simon Tchekmedyian, Lynn Navale, Rafael G. Amado, Neal J. Meropol

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 237 KB

english, 2007

8

Targeted lymph node evaluation in colorectal cancer: A decade of progress!

Anton J. Bilchik, Alexander Stojadinovic, Zev Wainberg, J. Randolph Hecht

Journal:

Journal of Surgical Oncology

Année:

2009

Langue:

english

Fichier:

PDF, 52 KB

english, 2009

9

A phase I and pharmacokinetic study of sunitinib administered daily for 2

Carolyn D. Britten, Fairooz Kabbinavar, J. Randolph Hecht, Carlo L. Bello, Jim Li, Charles Baum, Dennis Slamon

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2008

Langue:

english

Fichier:

PDF, 370 KB

english, 2008

10

Adjuvant therapy for gastric cancer: A reality at last

J. Randolph Hecht

Journal:

Current Gastroenterology Reports

Année:

2000

Langue:

english

Fichier:

PDF, 238 KB

english, 2000

11

Metastasis in colorectal cancer: what makes the tumor aggressive?

Joel Randolph Hecht

Journal:

European Journal of Surgery

Année:

1998

Langue:

english

Fichier:

PDF, 56 KB

english, 1998

12

The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers

Diaz Jr, Luis A., Williams, Richard T., Wu, Jian, Kinde, Isaac, Hecht, J. Randolph, Berlin, Jordan, Allen, Benjamin, Bozic, Ivana, Reiter, Johannes G., Nowak, Martin A., Kinzler, Kenneth W., Oliner, K

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 333 KB

english, 2012

13

Gastrin-Releasing Peptide-Induced Expression of Prostaglandin Synthase-2 in Swiss 3T3 Cells

J.Randolph Hecht, Javier Duque, Srinivasa T Reddy, Harvey R Herschman, John H Walsh, Lee W Slice

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 1.71 MB

english, 1997

14

Successful Gastrointestinal Cancer Drug Development

J. Randolph Hecht

Journal:

Seminars in Oncology

Année:

2006

Langue:

english

Fichier:

PDF, 211 KB

english, 2006

15

Improved imaging and the clinician: the role of positron emission tomography in the management of colorectal cancer

Joel Randolph Hecht

Journal:

Molecular Imaging and Biology

Année:

2004

Langue:

english

Fichier:

PDF, 99 KB

english, 2004

16

Immunohistochemical evaluation of K-ras, p53, and HER-2/neu expression in hyperplastic, dysplastic, and carcinomatous lesions of the pancreas: Evidence for multistep carcinogenesis

Sophia K Apple, J Randolph Hecht, David N Lewin, Soraya A Jahromi, Wayne W Grody, Roberta K Nieberg

Journal:

Human Pathology

Année:

1999

Langue:

english

Fichier:

PDF, 7.20 MB

english, 1999

17

Panitumumab with Irinotecan/Leucovorin/5-Fluorouracil for First-Line Treatment of Metastatic Colorectal Cancer

Jordan Berlin, James Posey, Simon Tchekmedyian, Eddie Hu, David Chan, Imtiaz Malik, Liqiang Yang, Rafael G. Amado, J. Randolph Hecht

Journal:

Clinical Colorectal Cancer

Année:

2009

Langue:

english

Fichier:

PDF, 1.38 MB

english, 2009

18

Bevacizumab plus oxaliplatin-based chemotherapy as adjuvant treatment for colon cancer (AVANT): a phase 3 randomised controlled trial

Aimery de Gramont, Eric Van Cutsem, Hans-Joachim Schmoll, Josep Tabernero, Stephen Clarke, Malcolm J Moore, David Cunningham, Thomas H Cartwright, J Randolph Hecht, Fernando Rivera, Seock-Ah Im, Györg

Journal:

The Lancet Oncology

Année:

2012

Langue:

english

Fichier:

PDF, 277 KB

english, 2012

19

A Novel Gene Transfer Therapy Against Pancreatic Cancer (TNFerade) Delivered by Endoscopic Ultrasound (EUS) and Percutaneous Guided Fine Needle Injection (FNI)

Kenneth J. Chang, Neil Senzer, Theodore Chung, J.Randolph Hecht, Stephen Vogel, Alexander Rosemurgy, John Nemunaitis, John Gibbs, Milind Javle, Tony Reid, Jennifer Macko, Paul Kessler, Mitchell C. Pos

Journal:

Gastrointestinal Endoscopy

Année:

2004

Langue:

english

Fichier:

PDF, 95 KB

english, 2004

20

EUS or percutaneously guided intratumoral TNFerade biologic with 5-fluorouracil and radiotherapy for first-line treatment of locally advanced pancreatic cancer: a phase I/II study

J. Randolph Hecht, James J. Farrell, Neil Senzer, John Nemunaitis, Alexander Rosemurgy, Theodore Chung, Nader Hanna, Kenneth J. Chang, Milind Javle, Mitchell Posner, Irving Waxman, Anthony Reid, Richa

Journal:

Gastrointestinal Endoscopy

Année:

2012

Langue:

english

Fichier:

PDF, 634 KB

english, 2012

21

Panitumumab with Irinotecan/Leucovorin/5-Fluorouracil for First-Line Treatment of Metastatic Colorectal Cancer

Jordan Berlin, James Posey, Simon Tchekmedyian, Eddie Hu, David Chan, Imtiaz Malik, Liqiang Yang, Rafael G. Amado, J. Randolph Hecht

Journal:

Clinical Colorectal Cancer

Année:

2007

Langue:

english

Fichier:

PDF, 153 KB

english, 2007

22

Association of K-ras Mutational Status and Clinical Outcomes in Patients with Metastatic Colorectal Cancer Receiving Panitumumab Alone

Daniel J. Freeman, Todd Juan, Maureen Reiner, J. Randolph Hecht, Neal J. Meropol, Jordan Berlin, Edith Mitchell, Ildiko Sarosi, Robert Radinsky, Rafael G. Amado

Journal:

Clinical Colorectal Cancer

Année:

2008

Langue:

english

Fichier:

PDF, 502 KB

english, 2008

23

A phase II trial of frontline capecitabine and bevacizumab in poor performance status and/or elderly patients with metastatic colorectal cancer

Naeim, Arash, Ward, Peter R., Wang, Hei-Jing, Dichmann, Richard, Liem, Andre K.D., Chan, David, Patel, Ravi, Hu, Edward H.L., Tchekmedyian, Neres S., Wainberg, Zev A., Hecht, J. Randolph

Journal:

Journal of Geriatric Oncology

Année:

2013

Langue:

english

Fichier:

PDF, 233 KB

english, 2013

24

3458 Tolerability and efficacy of direct injection of pancreatic adenocarcinomas with onyx-015 under endoscopic ultrasound (eus) guidance.

Bedford, Rudolph A., Hecht, J. Randolph, Lahoti, S., Abbruzzese, L., So, Lorreta, Kim, D.

Journal:

Gastrointestinal Endoscopy

Année:

2000

Langue:

english

Fichier:

PDF, 17 KB

english, 2000

25

Physical function and quality of life in frail and/or elderly patients with metastatic colorectal cancer treated with capecitabine and bevacizumab: An exploratory analysis

Ward, Peter, Hecht, J. Randolph, Wang, He-Jing, Dichmann, Richard, Liem, Andre K.D., Chan, David, Patel, Ravi, Hu, Edward H.L., Tchekmedyian, Neres S., Wainberg, Zev A., Naeim, Arash

Journal:

Journal of Geriatric Oncology

Année:

2014

Langue:

english

Fichier:

PDF, 334 KB

english, 2014

26

Panitumumab in colon cancer: a review and summary of ongoing trials

Wainberg, Zev, Hecht, J Randolph

Journal:

Expert Opinion on Biological Therapy

Année:

2006

Langue:

english

Fichier:

PDF, 240 KB

english, 2006

27

Panitumumab in colorectal cancer

Wainberg, Zev A, Hecht, J Randolph

Journal:

Expert Review of Anticancer Therapy

Année:

2007

Langue:

english

Fichier:

PDF, 297 KB

english, 2007

28

A Single Institution Experience in Compliance with Universal Screening for Lynch Syndrome in Colorectal Cancer

Hill, Amy L., Sumra, Kirandeep K., Russell, Marcia M., Yoo, James, Ko, Clifford Y., Hart, Steven, Wainberg, Zev, Hecht, J. Randolph, Lin, Anne Y.

Journal:

Journal of Gastrointestinal Surgery

Année:

2015

Langue:

english

Fichier:

PDF, 425 KB

english, 2015

29

Randomized, Placebo-Controlled, Phase III Study of Oxaliplatin, Fluorouracil, and Leucovorin With or Without PTK787/ZK 222584 in Patients With Previously Treated Metastatic Colorectal Adenocarcinoma

Van Cutsem, E., Bajetta, E., Valle, J., Kohne, C.-H., Randolph Hecht, J., Moore, M., Germond, C., Berg, W., Chen, B.-L., Jalava, T., Lebwohl, D., Meinhardt, G., Laurent, D., Lin, E.

Journal:

Journal of Clinical Oncology

Année:

2011

Langue:

english

Fichier:

PDF, 184 KB

english, 2011

30

Phase II trial of everolimus in patients with refractory metastatic adenocarcinoma of the esophagus, gastroesophageal junction and stomach: possible role for predictive biomarkers

Wainberg, Zev A., Soares, Heloisa P., Patel, Ravi, DiCarlo, Brian, Park, David J., Liem, Andre, Wang, He-jing, Yonemoto, Lisa, Martinez, Diego, Laux, Isett, Brennan, Meghan, Hecht, J. Randolph

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 1.00 MB

english, 2015

31

Extended RAS analysis for anti-epidermal growth factor therapy in patients with metastatic colorectal cancer

Hecht, J. Randolph, Douillard, Jean-Yves, Schwartzberg, Lee, Grothey, Axel, Kopetz, Scott, Rong, Alan, Oliner, Kelly S., Sidhu, Roger

Journal:

Cancer Treatment Reviews

Année:

2015

Langue:

english

Fichier:

PDF, 488 KB

english, 2015

32

Clinical development of talimogene laherparepvec (T-VEC): a modified herpes simplex virus type-1–derived oncolytic immunotherapy

Harrington, Kevin J., Puzanov, Igor, Hecht, J. Randolph, Hodi, F. Stephen, Szabo, Zsolt, Murugappan, Swami, Kaufman, Howard L.

Journal:

Expert Review of Anticancer Therapy

Année:

2015

Langue:

english

Fichier:

PDF, 932 KB

english, 2015

33

Polymerase Chain Reaction-Based K- ras Mutation Detection of Pancreatic Adenocarcinoma in Routine Cytology Smears

Apple, Sophia K., Hecht, J. Randolph, Novak, Jessica M., Nieberg, Roberta K., Rosenthal, Dorothy L., Grody, Wayne W.

Journal:

American Journal of Clinical Pathology

Année:

1996

Langue:

english

Fichier:

PDF, 1.64 MB

english, 1996

34

Genetics, epidemiology, prevention, and early detection of colorectal cancer

Hecht, J. Randolph

Journal:

Current Opinion in Gastroenterology

Année:

1997

Fichier:

PDF, 437 KB

1997

35

Association of Proton Pump Inhibitors and Capecitabine Efficacy in Advanced Gastroesophageal Cancer

Chu, Michael P., Hecht, J. Randolph, Slamon, Dennis, Wainberg, Zev A., Bang, Yung-Jue, Hoff, Paulo M., Sobrero, Alberto, Qin, Shukui, Afenjar, Karen, Houe, Vincent, King, Karen, Koski, Sheryl, Mulder,

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 286 KB

english, 2016

36

It Is Time to Stop Using Epirubicin to Treat Any Patient With Gastroesophageal Adenocarcinoma

Elimova, Elena, Janjigian, Yelena Y., Mulcahy, Mary, Catenacci, Daniel V., Blum, Mariela A., Almhanna, Khaldoun, Hecht, J. Randolph, Ajani, Jaffer A.

Journal:

Journal of Clinical Oncology

Année:

2017

Langue:

english

Fichier:

PDF, 631 KB

english, 2017

37

A Phase II, Randomized, Double‐Blind, Placebo‐Controlled Study of Simtuzumab in Combination with FOLFIRI for the Second‐Line Treatment of Metastatic KRAS Mutant Colorectal Adenocarcinoma

Hecht, J. Randolph, Benson, Al B., Vyushkov, Dmitry, Yang, Yingsi, Bendell, Johanna, Verma, Udit

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 325 KB

english, 2017

38

A Phase II Randomized, Double‐Blind, Placebo‐Controlled Study of Simtuzumab or Placebo in Combination with Gemcitabine for the First‐Line Treatment of Pancreatic Adenocarcinoma

Benson, Al B., Wainberg, Zev A., Hecht, J. Randolph, Vyushkov, Dmitry, Dong, Hua, Bendell, Johanna, Kudrik, Fred

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 327 KB

english, 2017

39

Final analysis of the randomised PEAK trial: overall survival and tumour responses during first-line treatment with mFOLFOX6 plus either panitumumab or bevacizumab in patients with metastatic colorectal carcinoma

Rivera, Fernando, Karthaus, Meinolf, Hecht, J. Randolph, Sevilla, Isabel, Forget, Frédéric, Fasola, Gianpiero, Canon, Jean-Luc, Guan, Xuesong, Demonty, Gaston, Schwartzberg, Lee S.

Journal:

International Journal of Colorectal Disease

Année:

2017

Langue:

english

Fichier:

PDF, 683 KB

english, 2017

40

Most intended management changes after 68 Ga-DOTATATE PET/CT are implemented

Calais, Jérémie, Czernin, Johannes, Eiber, Matthias, Fendler, Wolfgang Peter, Gartmann, Jeannine, Heaney, Anthony, Hendifar, Andrew, Pisegna, Joseph, Hecht, Joel Randolph, Wolin, Edward, Slavik, Roger

Journal:

Journal of Nuclear Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 737 KB

english, 2017

41

O-004Immunologic and objective tumor responses to PEGylated human IL-10 (AM0010) with 5-FU/LV and oxaliplatin (FOLFOX) in metastatic pancreatic adenocarcinoma (PDAC)

Hecht J., Randolph, Naing, Aung, Falchook, Gerald, Patel, Manish, Infante, Jeffrey, Aljumaily, Raid, Deborah, Wong, Autio, Karen, Wainberg, Zev, Javle, Milind, Bendell, Johanna, Pant, Shubham, Hung, A

Journal:

Annals of Oncology

Année:

2017

Langue:

english

Fichier:

PDF, 61 KB

english, 2017

42

A Randomized, Double-blind, Placebo-controlled Phase 2 Study of Ontuxizumab (MORAb-004) in Patients with Chemorefractory Metastatic Colorectal Cancer

Grothey, Axel, Strosberg, Jonathan R, Renfro, Lindsay A, Hurwitz, Herbert I., Marshall, John, Safran, Howard, Guarino, Michael J, Kim, George P., Hecht, J. Randolph, Weil, Susan C., Heyburn, John, Wan

Journal:

Clinical Cancer Research

Année:

2017

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2017

43

A Phase I, multicenter, open-label trial to evaluate the safety of talimogene laherparepvec (T-VEC) injected into liver tumors

Hecht, J Randolph, Raman, Steven, Sze, Daniel Y, Lockhart, A Craig, Moss, Rebecca A, Liu, Kate, Chou, Jeffrey, Reid, Tony

Journal:

Journal for ImmunoTherapy of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 214 KB

english, 2015

44

5-Fluorouracil, leucovorin, and oxaliplatin (mFOLFOX6) plus sunitinib or bevacizumab as first-line treatment for metastatic colorectal cancer: a randomized Phase IIb study

Hecht, J. Randolph, Mitchell, Edith, Yoshino, Takayuki, Welslau, Manfred, Lin, Xun, Maneval, Edna Chow, Paolini, Jolanda, Lechuga, Maria Jose, Kretzschmar, Albrecht

Journal:

Cancer Management and Research

Année:

2015

Langue:

english

Fichier:

PDF, 776 KB

english, 2015

45

VISUAL VIGNETTE

Yu, Run, Quon, Andrew, Hecht, J. Randolph

Journal:

Endocrine Practice

Année:

2017

Langue:

english

Fichier:

PDF, 436 KB

english, 2017

46

Talimogene laherparepvec: review of its mechanism of action and clinical efficacy and safety

Raman, Steven S, Hecht, Joel Randolph, Chan, Emily

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 3.59 MB

english, 2019

47

Threshold Change in CEA as a Predictor of Non-Progression to First-Line Systemic Therapy in Metastatic Colorectal Cancer Patients with Elevated CEA

Gulhati, Pat, Yin, Jun, Pederson, Levi, Schmoll, Hans-Joachim, Hoff, Paulo, Douillard, Jean-Yves, Hecht, J Randolph, Tournigand, Christophe, Tebbut, Niall, Chibaudel, Benoist, De Gramont, Aimery, Shi,

Journal:

JNCI Journal of the National Cancer Institute

Année:

2020

Langue:

english

Fichier:

PDF, 2.34 MB

english, 2020

48

Meta-analysis examining overall survival in patients with pancreatic cancer treated with second-line 5-fluorouracil and oxaliplatin-based therapy after failing first-line gemcitabine-containing therapy: effect of performance status and comparison with other regimens

Wainberg, Zev A., Feeney, Kynan, Lee, Myung Ah, MuÃ±oz, AndrÃ©s, GraciÃ¡n, Antonio Cubillo, Lonardi, Sara, Ryoo, Baek-Yeol, Hung, Annie, Lin, Yong, Bendell, Johanna, Hecht, J. Randolph

Journal:

Année:

2020

Fichier:

PDF, 886 KB

2020

49

Immunologic and tumor responses of pegilodecakin with 5-FU/LV and oxaliplatin (FOLFOX) in pancreatic ductal adenocarcinoma (PDAC)

Hecht, J. Randolph, Papadopoulos, Kyriakos P., Falchook, Gerald S., Patel, Manish R., Infante, Jeffrey R., Aljumaily, Raid, Wong, Deborah J., Autio, Karen A., Wainberg, Zev A., Bauer, Todd M., Javle,

Journal:

Investigational New Drugs

Année:

2020

Fichier:

PDF, 449 KB

2020